Liars in Research … a quest for the truth in medicine.

by John A. Baur, PT, DPT, OCS, CSCS, FAAOMPT

A record number of retractions are occurring in research due to falsified or fake research.
One lie that many Americans have heard over the years is that resveratrol in red wine is heart healthy. Dipak Das, PhD, a researcher from University of Connecticut Health Center, studied and published articles suggesting that 2 glasses of red wine a night is needed to maintain heart health. In 2012, the University of Connecticut announced that a review board found Dr. Das was guilty of 145 counts of fabrication or falsification of data and at least twenty of his research papers have been retracted.

A parallel study performed at Harvard University found that one would actually need to consume 2000 glasses of red wine a day to ingest enough resveratrol to have a health benefit. Furthermore, scientists at the Johns Hopkins University School of Medicine studied 800 men and women ages 65 and older whose diets were natural high in resveratrol and the study found there was no link between resveratrol levels and the rates of heart disease, cancer, and death (JAMA Internal Medicine).

Another fake and fraudulent article published in 1998 in the Lancet Journal showed an association between Autism and vaccination. This article was eventually retracted, however, currently in some states approximately 4% of children are not vaccinated due to fear of autism.

Vioxx, an anti-inflammatory medication thought to replace the need of people suffering from osteoarthritis from taking large doses of Ibuprofen, is another example of research being falsified. Researchers in the study of Vioxx were well aware of the cardiac challenges associated with taking Vioxx. They decided to selectively remove individuals’ cardiac abnormalities from their data and selectively  hired FDA employees as consultants to prevent negative information from being released to the public.

Duke University’s pharmacokinetics and cancer researcher Anil Potti, MD published that he had found a connection between a person’s genes and a pharmacokinetics cocktail. He built research around his reported findings and received 4 grants (2 of them Federal grants) for his research. However, parallel research conducted at MD Anderson Cancer Center showed that Dr. Potti’s work was all falsified. In 2015 Dr. Potti was found guilty, by U.S. Health and Human Services Department investigators, of engaging in misconduct while researching treatments in human cancer patients. Ultimately Duke University reached a settlement agreement with the federal health agency, patients, and the estates of patients who participated in those medical trials. Dr. Potti was allowed to continue research work, under supervision, until 2020, and Duke University currently has to go through additional steps since being caught for falsifying research on this occasion, and with other researchers.

These research retractions, from falsified and fraudulent studies, are never fully reported to the public or the medical community, and the long-term impact on society is significant.
Most published research findings have little pertinence whatsoever to clinical practice. With over 3 million biomedical publications occurring every year we are now in a race to identify who has a grasp of the best research and who doesn’t.

At Physical Therapy First we work hard as a practice to keep pace with the greatest and latest research, including retracted falsified studies, in order to glide our patients to optimal health and physical therapy outcomes. We also work hard to disseminate the best available medical information to our patients, residents, fellows and students.

Optimal Sleep Position to Prevent Pain and Headaches

by Maureen Ambrose, PT, DPT, OCS, COMT

Optimal Sleep Position

  • What position is best for sleep?
  • What kind of pillow should I be using?
  • I wake up with neck/back/hip pain or headaches.

These are questions and concerns that a physical therapist will discuss with nearly every type of patient. Although most common in spinal patients, sleep can be an issue with shoulder, hip, headache, and post-operative patients due to difficulty finding a position of comfort. When recovering from an injury, sleep is a crucial time of restoration and healing of injured tissues. If a patient is tossing and turning all night or waking up with pain, then they may be placing excessive strain on the affected body region during their sleep.

sleep position side

SLEEP POSITION: SIDE-SLEEPERS

Most of the following information is related to optimal positioning in the side-lying position, as the majority of people are side sleepers (for at least a portion of the night).

Starting at the neck, it is crucial for side sleepers to have a pillow that is high enough to span the distance between the shoulder and head. This will maintain a neutral cervical spine curve and prevent excessive forward shoulder positioning. Often, for those with broad shoulders, 2 pillows will be necessary or you may use the higher side of a contour pillow (as shown above). The chin should be slightly tucked down to prevent strain at the base of the head.

In the trunk, consider adding a small towel roll or bolster pillow to prop up your waist. The bolster will fit just below the ribs and above the hip bone, creating a neutral lumbar curve. This is especially helpful if you wake with mid or low back pain or have pain when turning in bed.

The above photo also shows a pillow between the knees, which keeps the pelvis from rotating.

Consider this option if you have lateral hip pain that limits how long you can sleep on your side.

BACK AND STOMACH SLEEPERS

Back sleepers make up the next most common position. A very small pillow under the knees can be helpful in those with acute back pain. However, this is not recommended as a long term solution as it can lead to hamstring muscle tightness.

Stomach sleepers make up the smallest percentage, and it is a position to avoid especially in lumbar and cervical spine patients diagnosed with stenosis or spondylolisthesis. A pillow under the trunk from hips to ribs is necessary to achieve a neutral spine. To avoid extreme neck rotation when on your stomach, consider placing your temple region on the end of the pillow and having your face angled towards the bed.

If you struggle with pain while trying to sleep or pain upon waking, discuss your concerns with your physical therapist. At Physical Therapy First, our thorough examination and evaluation allow the therapist to develop a customized treatment plan to improve your quality of life – including when you’re asleep.

Dizziness and Exercise Based Vestibular Rehab

Dizziness and Exercise Based Vestibular Rehab
By Sean Phillips PT, DPT, OCS

Millions of people suffer from dizziness every year, making even the simplest daily tasks difficult to perform. However, the word “dizzy” can accompany many different symptoms that someone can suffer from. Dizziness is a non-specific term used for the sense of imbalance, disorientation, vertigo, or light headedness. As we grow older our risk for encountering dizziness increases, and affects women at a higher rate than men. This is especially true when taking 3 or more forms of daily medication, as it is one of the most common side effects of combining medicine.

Feeling dizzy can lead to an increased risk of falls, heightened anxiety and fear levels, depression, and decreased activity levels. Due to this significant impact on daily activities, it is not surprising to learn that dizziness is one of the leading symptoms that would lead someone to seek care. But what can be done to help treat dizziness, especially if it has been going on for long periods of time?

Vestibular rehab has been attempting to treat patients with these complaints dating back to 1946, and today physical therapy is a leading provider for these services. These techniques have concentrated on identifying the causes of dizziness and correcting or reducing the impairments through specific exercises. In this article, we will briefly discuss several categories of dizziness and types of vestibular rehab that can treat specific disorders.

Categories of Dizziness

Vertigo
• True vertigo is a sense of rotation movement. This can feel like the room is spinning around you, or you are spinning around the room. It would be very similar to the sensation you get from someone suddenly stopping you from spinning in a chair, or a getting off a spinning theme park ride.
• Generally provoked by head movements, such as rolling over in bed or quickly looking upwards.
• BPPV = Benign Paroxysmal Positional Vertigo
• Tends to last less than 1 minute.

Disequilibrium
• Sense of poor balance or unsteadiness.
• Worse balance in dark rooms or when closing eyes, such as when washing your face in the shower.

Pre-syncope
• The sensation that someone is about to faint or pass out.
• Typically accompanied by nausea or sweating

Psycho-physiological
• Sensation like rocking on a boat, floating, or rocking

Vestibular Rehab

– VR exercises include eye, head, and body movements that stimulate the vestibular system with a goal of gradually returning a patient to their normal state.
– These exercises include habituation, adaptive strategies, or substitution techniques.
– Habituation exercises uses repetitive movements or provoking stimuli until patients no longer respond adversely to the stimuli.
• For example, if turning head increases dizziness, performing this motion in a controlled environment can gradually resolve the issue.
– Adaptation exercises focus on head movements while keeping eyes focused on a stationary target.
– Substitution exercises utilize the remaining sensory inputs your body has to aid postural control and decrease dizziness.

Conclusion:

In a systematic review of over 300 PT research articles, Kundakci et al. was able to conclude that vestibular rehab was beneficial in treating patients with chronic dizziness. These benefits included improvement in vertigo symptoms, fall risk, balance, confidence, and emotional status. However, they determined that it was not possible to identify the most effective vestibular rehab protocol, frequency, or intensity of exercises, attributing these changes to the high variability between patients.

Therefore, if you may be suffering from chronic dizziness then physical therapy and vestibular rehab may be of benefit to you. Since every patient’s symptoms may be slightly different, your physical therapist should be able to create a unique rehab program to return you to where you would like to be.

Kundakci B, Sultana A, Taylor AJ and Alshehri MA. How to cite this article: The effectiveness of exercise based vestibular rehabilitation in 2018, :276 (doi: adult patients with chronic dizziness: A systematic review [version 1; referees: 2 approved] F1000Research 7 )10.12688/f1000research.14089.1

Concussions and Post Concussion Syndrome

Concussions and Post Concussion Syndrome
By Lillian Byington PT, DPT, OCS, CMPT

Up to 3 million people each year seek medical treatment for concussions and concussion related symptoms; and further research indicates that up to half of people experiencing concussion do not report their symptoms. This suggests that up to 6 million people each year experience symptoms of concussion. While most people recover within a few weeks, 14-33% of patients complain of persistent symptoms 3+ months after injury. Current testing for concussion is limited. In the first 3 days after injury, there are some standardized assessments such as bloodwork, CT, and/or MRI which can be performed to diagnose concussion. These are often impractical and are not yet commonly used in the diagnosis or treatment of concussion.[/caption]

Once 4-5 days after injury have passed, there are no specific tests for concussion. Becoming more common is the use of physical therapy to treat the symptoms associated with concussions to maximize return to sport. Below we have summarized the most common symptoms and reviewed what physical therapy treatment addresses in order to treat patients.
Dizziness
60% of people suffering from concussion complain of dizziness. Physical therapy exam consists of testing your vision, how well you can track moving objects, balance, and inner ear function. Once we know which aspects are contributing to symptoms of dizziness, we can design a treatment program to help address any deficits you may have
Memory loss and/or exercise intolerance
Memory loss and exercise intolerance seem to be correlated in patients after concussion. Research suggests that this is due to cerebral blood flow changes in the first 3 days after injury. While these symptoms can persist for weeks to months, blood flow changes seem to resolve within the first 3 days. We use a combination of endurance/cardiovascular tests and patient reported symptoms to design a gradual exercise program to minimize these symptoms
Visual disturbances
42-55% of patients note visual disturbances after concussion. A full exam to test your vision and how well you track moving objects can help differentiate these symptoms from dizziness. Once we know which aspects are contributing to your symptoms, we can design a treatment program to help address any deficits you may have
Mood changes/anxiety
25% of patients with concussion report new symptoms of anxiety and mood changes. These are usually assessed with patient history and subjective reports
Migraine headache
70% of patients with concussion report new onset of migraine headaches. There is an international classification criteria to diagnose migraine vs headache. A full exam of your neck will also help us determine what is causing your headaches. Once we know what your deficits are, we can coordinate with your doctor and/or treat any physical impairments we have found in order to reduce your headache.
Neck pain
Neck pain can also contribute to headaches and dizziness. A full neck exam, visual exam, and balance screen can help us determine what specifically is causing your symptoms and allow us to design a treatment plan to address your specific issues to help you feel better
Cognitive deficits
Changes in mental function are some of the first diagnosis tools we had for concussion. Studies suggest these deficits can last days to months. While pre-injury baseline testing is useful, it is not necessary. We use a combination of patient history and dynamic balance/memory tests to help determine what your deficits are and incorporate them into your treatment plan

Recovery from concussions

Clinical recovery from a concussion (what the patient reports as their symptoms) is often very different from physiological recovery from concussion. We know changes in electrical response, metabolic balance, and oxygen consumption persist for several months after a patient’s clinical testing comes back normal and patients report being symptom free. We base most of our return to activity on the clinical tests listed above, and patient reports of symptoms.
Allowing clinical signs to completely resolve before returning to sport not only reduces the risk for future concussion, but also reduces the risk of other injury.

What does this mean for me?

If you have been diagnosed with a concussion OR if you feel that you may have suffered a concussion, and are still dealing with side effects, physical therapy can help. Here at PT First we focus on what your symptoms are and how they affect you, and use that to guide our examination and treatment plan so we can get you back to your activities.

Original Article – Diagnosis and Management of Concussion

Mucha, Anne, and Alicia Trbovich. “Considerations for Diagnosis and Management of Concussion.” Journal of Orhopaedic and Sports Physical Therapy, vol. 49, ser. 11, Nov. 2019, pp. 787–798. 11.

Dry Needling Treatment – How it Works

Dry Needling Treatment Explained
by Logan Swisher SPT

How is Dry Needling treatment applied?

Dry needling treatment has become an increasingly popular treatment technique performed by certified health care providers. It refers to the insertion of a very thin needle into muscles, ligaments, tendons, subcutaneous fascia, and/or scar tissue for the management of numerous musculoskeletal pain syndromes.

Trigger points

There are several advantages to the technique documented in the literature which include an immediate reduction in local and /or widespread pain, restoration of range of motion and normalization of chemical imbalances with active myofascial trigger points. A trigger point is a hyperirritable spot often referred to “a knot” in the muscle or fascia which can cause pinpoint pain in the or refer to another area in the body. Trigger points can further be divided into active and latent trigger points. Active trigger points commonly have spontaneous local and referred pain while latent trigger points do not cause spontaneous pain unless they are stimulated by pressure.

How are trigger points formed?

The exact mechanism of trigger point formation is not well understood but it is thought that it starts as the development of tight muscle fibers or taut bands which may or may not be painful. This is possibly due to chemical reaction dysfunction at the cellular level of muscle fibers. Trigger points are thought to develop following low-load repetitive tasks, sustained postures or rapid loading and unloading of muscles. Initially taut band formation is a normal physiologic, protective and stabilizing mechanism associated with damage or potential muscle damage. Active trigger points produce constant pain signals to the brain which can alter movement patterns and lead to disuse. Trigger points have also been seen to cause decreased blood flow and oxygen to the affect muscle which further decreases the muscles ability to function properly.

Differences between dry needling treatment and manual trigger point release

The main difference between dry needling and manual trigger point release is the specificity dry needling provides. Dry needling latent trigger points can lead to their inactivation and prevent the formation of active trigger points as well as reduce the pain signals they produce. It is rarely a stand-alone treatment and is generally considered another instrument assisted manual therapy technique. Dry needling can be very useful in facilitating a rapid reduction of pain and return to function.

How it is applied at Physical Therapy First

Here at PTFirst we will perform a comprehensive exam and work with you to decide if dry needling is a good option for you. We pride ourselves on taking a multimodal approach to reducing pain and improving function so you can return to the activities that are important to you.

Can Physical Therapy help my Headache?

By Maureen Ambrose PT, DPT, OCS

INTRO

Headaches are a common complaint for many people, and most assume that it is just normal part of life. Some may experience headaches multiple times per week or even daily. Patients often report that headache medication may help reduce the severity of the symptoms, but does not eliminate them entirely or stop them from coming back.  If this is true for you, it may be a sign that your headaches are related to dysfunction in your neck. Both tension headache and the various forms of migraine headaches will likely have a musculoskeletal component.

CERVICOGENIC HEADACHE

The term “cervicogenic headache” indicates that although pain is felt in the head, the root cause of the symptoms related to the neck (cervical spine). Common root causes of head and facial pain include:

– Altered cervical spine alignment

– Forward head posture

– Muscle tightness or trigger points in the following muscles (see figure above)

– Upper Trapezius

– Suboccipitals

– Sternocleidomastoid

– Splenius capitus and Splenius cervicis

– Shallow breathing pattern using the neck muscles

– Jaw clenching or grinding

STRESS

 Now, what about those who just attribute their headaches to work-life stress? While it may be true that the headache feels worse during times of stress, it could be related to some of the root causes listed above. During a stressful meeting, do you resort to a shallow breathing pattern and overwork the neck muscles? Or, while concentrating on work, are you holding tension in your jaw or facial muscles and clenching? Each of these, over time and with repetition, has the potential to create trigger points in the neck muscles that can lead to referred pain in the head and face.

Physical Therapy for headaches begins with an exam of your neck alignment, posture, muscle strength, and breathing pattern. Treatment involves postural correction and neck strengthening, releasing trigger points, correcting breathing patterns, and improving postural and muscle awareness. If you feel that these factors could be a cause of your headaches, Physical Therapy First can help identify and treat these issues.

RED FLAGS

There are times when the headache is more than “cervicogenic,” and the following red flags from The Amercian Migraine Foundation indicate the need for medical attention:

  1. Thunderclap Headache: very severe headache that reaches its maximum severity immediately (within a couple of minutes). Thunderclap headaches require emergent medical evaluation.
  2. Positional Headache: headache that substantially changes in intensity in association with changes in position – e.g. standing from lying or vice-versa.
  3. Headaches Initiated by Exertion: headache starting while coughing, sneezing, and/or straining.
  4. New Headaches: especially if older than 50 years of age, or if there are medical conditions that make worrisome headaches more likely (e.g. cancer, blood clotting disorder).
  5. Substantial Change in Headache Pattern
  6. Constant Headache Always in the Same Location of the Head
  7. Worrisome Neurologic Symptoms: about 1/3 of people with migraine have neurologic symptoms (“migraine aura”) that typically precede onset of a migraine headache. Commonly, aura symptoms consist of slowly spreading visual symptoms sometimes accompanied by tingling of the face and upper extremity. These symptoms resolve within 60 minutes. If these symptoms have immediate onset (as opposed to a slow progression of symptoms), last longer than 60 minutes, or do not completely resolve, medical attention is required. Medical attention is also required if other symptoms are present, such as weakness of one side of the body, change in level of consciousness, significant difficulty walking, or other symptoms that worry you.
  8. Headache that never goes away
  9. Systemic symptoms: including fever, chills, weight loss, night sweats

SOURCES

(1)Travell JG, Simons DG. Myofascial Pain and Dysfunction, The Trigger Point Manual, Vol. 1. Baltimore. Williams and Wilkins. 1993

(2) American Migraine Foundation