Running with Knee Osteoarthritis-Part 3

By Lillian Wynn PT, DPT
Physical Therapist


40% of American adults (110 million people) report walking or running as part of a regular exercise routine.  Reports and ‘common knowledge’ about running and its impact on our joints are often conflicting. This is the third of three blog posts designed to look at current medical research regarding running on aging joints.

Article summary


This paper is a systematic review and meta-analysis, so the authors compiled research on knee osteoarthritis (OA) and running, and summarized the findings in order to provide a concise recommendation based on the general consensus of research. Articles were included if they: were level I-III evidence, written in English, used physician diagnosed OA with clinical and/or radiographic findings, and running was compared to non-running. Articles that compared running to other forms of exercises were not included in this study.


Literature searches were performed, and 1,907 articles were reviewed. Of those, 25 met their inclusion criteria. Statistical analysis was performed on those 25 studies to come to a meta-analysis, which summarizes and confirms the general recommendations based on significant research.


The authors concluded that recreational running was in fact associated with lower levels of OA when compared to sedentary individuals. Competitive running was associated with higher levels of OA than recreational runners. Overall, sedentary subject demonstrated the most symptomatic OA. The study also argues that this simply compares runners to non-runners. So the only conclusion that can be drawn is that running is better than being sedentary. More research should be done into seeing if running vs other forms of exercise is the best for of exercise.

 PTF approach

Here at PTF, we want to keep you active in the activities that matter to you. If walking and running are important to you, and you feel limited by your knees, an evaluation could be useful. There are many factors besides osteoarthritis that could be contributing to your knee pain while running. PTF does a complete evaluation and then designs a treatment plan individual to you and your body to keep you moving.

Original Article

Alentorn-Geli, E., Samuelsson, K., Musahl, V., Green, C., Bhandari, M., Karlsson, J. (2017). The Association of Recreational and Competitive Running with Hip and Knee Osteoarthritis: Systematic Review and Meta-analysis. J Orthop Sports Phys Ther, 47(6), 373-390. doi:10.2519/jospt.2017.7137

What are the Risk Factors for Reinjury Following an ACL Reconstruction?

by Alex Tan, PT, DPT OCS
Physical Therapist


Anterior cruciate ligament (ACL) rupture rate is the highest in young athletes who participate in sports involving cutting and pivoting (basketball, skiing, soccer) and when they occur tend to be season-ending injuries requiring surgical reconstruction. Female sex and young age have been viewed as common risk factors for initial injury. Even after successful surgical reconstruction and rehabilitation, reinjury to the reconstructed ACL and/or ACL of the opposite limb can occur. At this time, research suggests that environmental and genetic factors may be causes of reinjury. Recently, more studies have become available focusing on the rates of reinjury in younger active individuals, but their results have not been summarized.

Literature search and data analysis to determine possible risk factors for reinjury:

In a recent article by Wiggins et al researchers reviewed existing literature and analyzed data found within to evaluate whether a patient’s age and activity level could be seen as risk factors for another ACL injury following reconstruction.

The researchers narrowed down a database search to 19 articles for review. Then they recorded data from populations included in these articles regarding: total ACL reinjury rate (of the same side and/or opposite limb), specific sport an individual returned to if provided, the nature of the sport (low risk or high-risk involving cutting/jumping), and demographics.

The researchers hypothesized that returning to sport and a younger age would place individuals at higher risk for a second ACL injury.

An analysis was performed on the data from the entire included population and a separate analysis was performed on data sets broken down by individuals of a young age, those who returned to a sport, and from those who were young and returned to a sport.


  • In individuals across all ages who underwent ACL reconstruction: 7% reinjured the same ACL and 8% reinjured the opposite side
  • In individuals < 25 years old who underwent ACL reconstruction: 21% had another ACL injury with 11% being the opposite knee
  • In individuals who returned to sports following reconstruction: 20% had another ACL injury with 12% being the opposite knee
  • In individuals who were <25 years old who returned to high-risk sport following reconstruction: 23% had another injury with 12%

ACL Reinjury Data Graph


Individuals who return to a high-risk sport and those of a younger age are at risk for ACL reinjury. Almost one-fourth of individuals who are of a younger age (<20-25) and return to a high risk sport that involves pivoting and cutting will either reinjure the reconstructed ACL or injure the opposite side. Based on the current literature the majority of these secondary injuries occur in the knee that has not undergone previous surgical intervention.

What Can Physical Therapists Do to Prevent Reinjury?

Individuals who have or have not undergone a previous ACL repair can be examined by a physical therapist who can determine if they are at risk for injury/reinjury due to factors such as:

  • The individual’s improper performance of functional movements
  • Muscular imbalances
  • Strength and flexibility deficits
  • Improper running and landing mechanics
  • Balance deficits
  • Asymmetrical strength/power between limbs

Your therapist will then address these issues with a personalized plan of care which may include but is not limited to interventions such as:

  • Exercises to strengthen or improve flexibility in specific muscles
  • Plyometric or jump training
  • Activity modification recommendations
  • Neuromuscular re-education
  • Bracing

Original Article: Wiggins Amelia, Grandhi Ravi, Schneider Daniel, Stanfield Denver, Webster Kate, Myer Gregory. Risk of secondary injury in younger athletes after anterior cruciate ligament reconstruction: A systematic review and meta-analysis Am J. Sports Med. 2016 July; 44(&): 1861-1876