By John Baur, PT, DPT, OCS, FAAOMPT

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that affects millions of people worldwide. It is characterized by symptoms such as abdominal pain, bloating, and changes in bowel habits. While the exact cause of IBS is unknown, it is believed to be related to an imbalance in the gut microbiota and inflammation. In recent years, there has been growing interest in the use of probiotics and other microbiota-targeted therapies for the treatment of IBS. In this report, we will discuss the potential of Bacillus spp. spores as a promising treatment option for patients with IBS.

Bacillus spp. Spores and Gut Microbiota

Bacillus spp. are a group of spore-forming bacteria that are commonly found in soil and water. They are known for their ability to survive in harsh environments and have been used for centuries in traditional medicine for the treatment of various ailments. In recent years, there has been growing interest in the use of Bacillus spp. spores as a probiotic for the treatment of gastrointestinal disorders.

Studies have shown that Bacillus spp. spores have the ability to modulate the gut microbiota and reduce inflammation. They have been shown to increase the abundance of beneficial bacteria such as Bifidobacterium and Lactobacillus, while reducing the abundance of harmful bacteria such as Clostridium difficile. Bacillus spp. spores also produce short-chain fatty acids (SCFAs), which are important for maintaining gut health and reducing inflammation.

Bacillus spp. Spores and Irritable Bowel Syndrome

Several studies have investigated the potential of Bacillus spp. spores as a treatment option for patients with IBS. A randomized, double-blind, placebo-controlled trial found that a combination of Bacillus coagulans and fructooligosaccharides (FOS) significantly improved symptoms of IBS, including abdominal pain, bloating, and stool consistency. Another study found that Bacillus clausii spores significantly reduced symptoms of IBS, including abdominal pain and bloating.

The mechanism by which Bacillus spp. spores improve symptoms of IBS is not fully understood. However, it is believed that their ability to modulate the gut microbiota and reduce inflammation plays a key role. Bacillus spp. spores may also improve gut barrier function, which is important for preventing the entry of harmful bacteria and toxins into the bloodstream.

In conclusion, Bacillus spp. spores have shown promising results as a treatment option for patients with irritable bowel syndrome (IBS). Studies have shown that Bacillus spp. spores have the ability to modulate the gut microbiota and reduce inflammation, which are key factors in the development of IBS. Bacillus spp. spores have been shown to improve symptoms of IBS, including abdominal pain, bloating, and stool consistency. While more research is needed to fully understand the mechanism by which Bacillus spp. spores improve symptoms of IBS, they offer a promising treatment option for patients who do not respond to traditional therapies. Bacillus spp. spores are generally safe and well-tolerated, making them a viable option for long-term use.

Physical Therapy First recognizes the importance staying well-informed with the latest health and wellness topics that affect our patients.  Megasporebiotic made by Microbiome Labs (microbiomelabs.com) is the first spore-base probiotic with research which supports it use for IBS and many other health conditions. 

Reference

Bacillus spp. Spores-A Promising Treatment Option for Patients with Irritable Bowel Syndrome.

Catinean A, Neag AM, Nita A, Buzea M, Buzoianu AD.Nutrients. 2019 Aug 21;11(9):1968. doi: 10.3390/nu11091968.